The San Francisco 49ers are wrapping up their preseason schedule with a battle against the Las Vegas Raiders at Allegiant Stadium on Thursday.
Unfortunately, the 49ers lost one of their 2026 draft picks in the first quarter of the exhibition matchup, as cornerback Ephesians Prysock suffered a shoulder injury was originally listed as questionable to return. He's now been ruled out.
Prysock, 23, played collegiately at Arizona (2022-23) and Washington (2024-25) before San Francisco took him in the fourth round (No. 139 overall) of this year's draft. He's popped a bit in the team's first two preseason games, so this actually is a big loss for this contest, especially considering the starters aren't playing.
If Prysock can't go, the 49ers will have to rely on Jack Jones, Jakob Robinson, Eli Apple and Darrell Luter Jr. at cornerback for the rest of the game.
More 49ers: 49ers vs. Raiders live updates: Preseason game start time, TV channel
This article originally appeared on Niners Wire: Promising 49ers rookie ruled out vs. Raiders after early injury
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